{"id":14106,"date":"2024-01-11T08:45:56","date_gmt":"2024-01-11T01:45:56","guid":{"rendered":"https:\/\/science.mahidol.ac.th\/simple-science\/?p=14106"},"modified":"2024-02-22T10:01:05","modified_gmt":"2024-02-22T03:01:05","slug":"pls-183","status":"publish","type":"post","link":"https:\/\/science.mahidol.ac.th\/simple-science\/2024\/01\/11\/pls-183\/","title":{"rendered":"\u0e19\u0e31\u0e01\u0e27\u0e34\u0e08\u0e31\u0e22\u0e40\u0e1c\u0e22\u0e40\u0e17\u0e04\u0e19\u0e34\u0e04 \u0e43\u0e0a\u0e49\u0e22\u0e32\u0e2d\u0e22\u0e48\u0e32\u0e07\u0e44\u0e23 \u0e0a\u0e48\u0e27\u0e22\u0e22\u0e31\u0e1a\u0e22\u0e31\u0e49\u0e07\u0e40\u0e0b\u0e25\u0e25\u0e4c\u0e21\u0e30\u0e40\u0e23\u0e47\u0e07\u0e40\u0e21\u0e47\u0e14\u0e40\u0e25\u0e37\u0e2d\u0e14\u0e02\u0e32\u0e27 \u0e44\u0e14\u0e49\u0e14\u0e35\u0e17\u0e35\u0e48\u0e2a\u0e38\u0e14!!"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"14106\" class=\"elementor elementor-14106\">\n\t\t\t\t<div class=\"elementor-element elementor-element-13dee6cd e-flex e-con-boxed e-con e-parent\" data-id=\"13dee6cd\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-11c1be16 elementor-widget elementor-widget-image\" data-id=\"11c1be16\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"5000\" height=\"2617\" src=\"https:\/\/science.mahidol.ac.th\/simple-science\/wp-content\/uploads\/2024\/01\/2.png\" class=\"attachment-full size-full wp-image-14303\" alt=\"\" srcset=\"https:\/\/science.mahidol.ac.th\/simple-science\/wp-content\/uploads\/2024\/01\/2.png 5000w, https:\/\/science.mahidol.ac.th\/simple-science\/wp-content\/uploads\/2024\/01\/2-300x157.png 300w, https:\/\/science.mahidol.ac.th\/simple-science\/wp-content\/uploads\/2024\/01\/2-768x402.png 768w, https:\/\/science.mahidol.ac.th\/simple-science\/wp-content\/uploads\/2024\/01\/2-1536x804.png 1536w, https:\/\/science.mahidol.ac.th\/simple-science\/wp-content\/uploads\/2024\/01\/2-2048x1072.png 2048w, https:\/\/science.mahidol.ac.th\/simple-science\/wp-content\/uploads\/2024\/01\/2-700x366.png 700w\" sizes=\"(max-width: 5000px) 100vw, 5000px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-534cfcc6 e-con-full e-flex e-con e-parent\" data-id=\"534cfcc6\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-cbd3232 e-con-full e-flex e-con e-child\" data-id=\"cbd3232\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-7b910cf1 elementor-widget elementor-widget-image\" data-id=\"7b910cf1\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/science.mahidol.ac.th\/simple-science\/wp-content\/uploads\/2024\/01\/sorafenib-image2-Alisa-Damnernsawad.png\" data-elementor-open-lightbox=\"yes\" data-elementor-lightbox-title=\"sorafenib image2 - Alisa Damnernsawad\" data-e-action-hash=\"#elementor-action%3Aaction%3Dlightbox%26settings%3DeyJpZCI6MTQxMTksInVybCI6Imh0dHBzOlwvXC9zY2llbmNlLm1haGlkb2wuYWMudGhcL3NpbXBsZS1zY2llbmNlXC93cC1jb250ZW50XC91cGxvYWRzXC8yMDI0XC8wMVwvc29yYWZlbmliLWltYWdlMi1BbGlzYS1EYW1uZXJuc2F3YWQucG5nIn0%3D\">\n\t\t\t\t\t\t\t<img decoding=\"async\" width=\"1060\" height=\"1207\" src=\"https:\/\/science.mahidol.ac.th\/simple-science\/wp-content\/uploads\/2024\/01\/sorafenib-image2-Alisa-Damnernsawad.png\" class=\"attachment-large size-large wp-image-14119\" alt=\"\" srcset=\"https:\/\/science.mahidol.ac.th\/simple-science\/wp-content\/uploads\/2024\/01\/sorafenib-image2-Alisa-Damnernsawad.png 1064w, https:\/\/science.mahidol.ac.th\/simple-science\/wp-content\/uploads\/2024\/01\/sorafenib-image2-Alisa-Damnernsawad-263x300.png 263w, https:\/\/science.mahidol.ac.th\/simple-science\/wp-content\/uploads\/2024\/01\/sorafenib-image2-Alisa-Damnernsawad-768x875.png 768w, https:\/\/science.mahidol.ac.th\/simple-science\/wp-content\/uploads\/2024\/01\/sorafenib-image2-Alisa-Damnernsawad-700x797.png 700w\" sizes=\"(max-width: 1060px) 100vw, 1060px\" \/>\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-1206e97a e-con-full e-flex e-con e-child\" data-id=\"1206e97a\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-5d0b0519 elementor-widget__width-initial elementor-widget-mobile__width-initial elementor-widget elementor-widget-image\" data-id=\"5d0b0519\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"150\" height=\"150\" src=\"https:\/\/science.mahidol.ac.th\/simple-science\/wp-content\/uploads\/2024\/01\/247-1-150x150.jpg\" class=\"attachment-thumbnail size-thumbnail wp-image-14123\" alt=\"\" srcset=\"https:\/\/science.mahidol.ac.th\/simple-science\/wp-content\/uploads\/2024\/01\/247-1-150x150.jpg 150w, https:\/\/science.mahidol.ac.th\/simple-science\/wp-content\/uploads\/2024\/01\/247-1.jpg 300w\" sizes=\"(max-width: 150px) 100vw, 150px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1c62806d elementor-widget elementor-widget-qi_addons_for_elementor_info_button\" data-id=\"1c62806d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"qi_addons_for_elementor_info_button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<a class=\"qodef-shortcode qodef-m qodef-qi-info-button qodef-html--link qodef-layout--filled qodef-type--standard qodef-icon--right qodef-hover--icon-move-horizontal-short\" href=\"https:\/\/science.mahidol.ac.th\/expertise\/search_th.php?q=%E0%B8%AD%E0%B8%A5%E0%B8%B4%E0%B8%AA%E0%B8%B2%20%E0%B8%94%E0%B8%B3%E0%B9%80%E0%B8%99%E0%B8%B4%E0%B8%99%E0%B8%AA%E0%B8%A7%E0%B8%B1%E0%B8%AA%E0%B8%94%E0%B8%B4%E0%B9%8C\" target=\"_self\">\n\t<div class=\"qodef-m-text-holder\">\n\t<span class=\"qodef-m-text\">\u0e1c\u0e28. \u0e14\u0e23.\u0e2d\u0e25\u0e34\u0e2a\u0e32 \u0e14\u0e33\u0e40\u0e19\u0e34\u0e19\u0e2a\u0e27\u0e31\u0e2a\u0e14\u0e34\u0e4c<\/span>\n\t\t\t<span class=\"qodef-m-icon\">\n\t\t<span class=\"qodef-m-icon-inner\">\n\t\t\t<i aria-hidden=\"true\" class=\"fas fa-comments\"><\/i>\t\t\t\t\t<\/span>\n\t<\/span>\n\t<\/div>\n\t\t\t<span class=\"qodef-m-subtext\">\u0e20\u0e32\u0e04\u0e27\u0e34\u0e0a\u0e32\u0e0a\u0e35\u0e27\u0e27\u0e34\u0e17\u0e22\u0e32<\/span>\n\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2231322f elementor-widget elementor-widget-heading\" data-id=\"2231322f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<p class=\"elementor-heading-title elementor-size-default\">\u0e1c\u0e39\u0e49\u0e14\u0e33\u0e40\u0e19\u0e34\u0e19\u0e01\u0e32\u0e23\u0e23\u0e48\u0e27\u0e21<\/p>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-27fdaddf e-con-full e-flex e-con e-child\" data-id=\"27fdaddf\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-3a9bb310 elementor-widget elementor-widget-qi_addons_for_elementor_info_button\" data-id=\"3a9bb310\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"qi_addons_for_elementor_info_button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<a class=\"qodef-shortcode qodef-m qodef-qi-info-button qodef-html--link qodef-layout--filled qodef-type--standard qodef-icon--right qodef-hover--icon-move-horizontal-short\" href=\"\" target=\"_self\">\n\t<div class=\"qodef-m-text-holder\">\n\t<span class=\"qodef-m-text\">Jeffrey W. Tyner<\/span>\n\t\t\t<span class=\"qodef-m-icon\">\n\t\t<span class=\"qodef-m-icon-inner\">\n\t\t\t<i aria-hidden=\"true\" class=\"fas fa-user\"><\/i>\t\t\t\t\t<\/span>\n\t<\/span>\n\t<\/div>\n\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3458ef87 elementor-widget elementor-widget-qi_addons_for_elementor_info_button\" data-id=\"3458ef87\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"qi_addons_for_elementor_info_button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<a class=\"qodef-shortcode qodef-m qodef-qi-info-button qodef-html--link qodef-layout--filled qodef-type--standard qodef-icon--right qodef-hover--icon-move-horizontal-short\" href=\"\" target=\"_self\">\n\t<div class=\"qodef-m-text-holder\">\n\t<span class=\"qodef-m-text\">Tamilla Nechiporuk<\/span>\n\t\t\t<span class=\"qodef-m-icon\">\n\t\t<span class=\"qodef-m-icon-inner\">\n\t\t\t<i aria-hidden=\"true\" class=\"fas fa-user\"><\/i>\t\t\t\t\t<\/span>\n\t<\/span>\n\t<\/div>\n\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-415befc0 e-con-full e-flex e-con e-child\" data-id=\"415befc0\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-6077b3d1 elementor-widget elementor-widget-heading\" data-id=\"6077b3d1\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">\u0e01\u0e32\u0e23\u0e28\u0e36\u0e01\u0e29\u0e32 Genome-wide CRISPR screen \u0e23\u0e30\u0e1a\u0e38\u0e15\u0e31\u0e27\u0e04\u0e27\u0e1a\u0e04\u0e38\u0e21\u0e01\u0e32\u0e23\u0e17\u0e33\u0e07\u0e32\u0e19\u0e02\u0e2d\u0e07 MAPK \u0e41\u0e25\u0e30 MTOR pathways \u0e17\u0e33\u0e2b\u0e19\u0e49\u0e32\u0e17\u0e35\u0e48\u0e40\u0e1b\u0e47\u0e19\u0e15\u0e31\u0e27\u0e01\u0e33\u0e2b\u0e19\u0e14\u0e01\u0e32\u0e23\u0e14\u0e37\u0e49\u0e2d\u0e22\u0e32 sorafenib \u0e43\u0e19\u0e21\u0e30\u0e40\u0e23\u0e47\u0e07\u0e40\u0e21\u0e47\u0e14\u0e40\u0e25\u0e37\u0e2d\u0e14\u0e02\u0e32\u0e27\u0e41\u0e1a\u0e1a\u0e40\u0e09\u0e35\u0e22\u0e1a\u0e1e\u0e25\u0e31\u0e19\u0e0a\u0e19\u0e34\u0e14\u0e21\u0e31\u0e22\u0e2d\u0e35\u0e25\u0e2d\u0e22\u0e14\u0e4c<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-6cc8bc3e e-con-full e-flex e-con e-child\" data-id=\"6cc8bc3e\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-4b5780be elementor-widget elementor-widget-heading\" data-id=\"4b5780be\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h5 class=\"elementor-heading-title elementor-size-default\">A genome-wide CRISPR screen identifies regulators of MAPK and MTOR pathways that mediate resistance to sorafenib in acute myeloid leukemia<\/h5>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-77fa2bfb elementor-widget elementor-widget-qi_addons_for_elementor_separator\" data-id=\"77fa2bfb\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"qi_addons_for_elementor_separator.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"qodef-shortcode qodef-m qodef-qi-separator qodef-qi-clear qodef-separator--standard qodef-position--left\">\n\t<div class=\"qodef-m-line\"><\/div>\n<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-47747d32 elementor-widget elementor-widget-text-editor\" data-id=\"47747d32\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>\u00a0 \u00a0 \u00a0 \u00a0\u0e42\u0e23\u0e04\u0e21\u0e30\u0e40\u0e23\u0e47\u0e07\u0e40\u0e21\u0e47\u0e14\u0e40\u0e25\u0e37\u0e2d\u0e14\u0e02\u0e32\u0e27\u0e41\u0e1a\u0e1a\u0e40\u0e09\u0e35\u0e22\u0e1a\u0e1e\u0e25\u0e31\u0e19\u0e0a\u0e19\u0e34\u0e14\u0e21\u0e31\u0e22\u0e2d\u0e35\u0e25\u0e2d\u0e22\u0e14\u0e4c\u0e19\u0e31\u0e49\u0e19\u0e21\u0e35\u0e01\u0e32\u0e23\u0e14\u0e33\u0e40\u0e19\u0e34\u0e19\u0e02\u0e2d\u0e07\u0e42\u0e23\u0e04\u0e40\u0e23\u0e47\u0e27\u0e41\u0e25\u0e30\u0e2d\u0e31\u0e15\u0e23\u0e32\u0e01\u0e32\u0e23\u0e23\u0e2d\u0e14\u0e0a\u0e35\u0e27\u0e34\u0e15\u0e15\u0e48\u0e33<\/strong> 30% \u0e02\u0e2d\u0e07\u0e1c\u0e39\u0e49\u0e1b\u0e48\u0e27\u0e22\u0e21\u0e35<strong>\u0e04\u0e27\u0e32\u0e21\u0e1c\u0e34\u0e14\u0e1b\u0e01\u0e15\u0e34\u0e02\u0e2d\u0e07\u0e22\u0e35\u0e19 <\/strong><strong>FLT3<\/strong> \u0e0b\u0e36\u0e48\u0e07\u0e17\u0e33\u0e43\u0e2b\u0e49\u0e42\u0e1b\u0e23\u0e15\u0e35\u0e19 <strong>FLT3<\/strong> \u0e17\u0e33\u0e07\u0e32\u0e19\u0e21\u0e32\u0e01\u0e40\u0e01\u0e34\u0e19\u0e44\u0e1b \u0e14\u0e31\u0e07\u0e19\u0e31\u0e49\u0e19\u0e40\u0e23\u0e32\u0e08\u0e36\u0e07\u0e21\u0e35\u0e04\u0e27\u0e32\u0e21\u0e1e\u0e22\u0e32\u0e22\u0e32\u0e21\u0e43\u0e19\u0e01\u0e32\u0e23\u0e1e\u0e31\u0e12\u0e19\u0e32\u0e22\u0e32\u0e17\u0e35\u0e48\u0e2a\u0e32\u0e21\u0e32\u0e23\u0e16\u0e22\u0e31\u0e1a\u0e22\u0e31\u0e49\u0e07\u0e01\u0e32\u0e23\u0e17\u0e33\u0e07\u0e32\u0e19\u0e02\u0e2d\u0e07 <strong>FLT3<\/strong> \u0e44\u0e14\u0e49<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4d32c080 elementor-widget elementor-widget-text-editor\" data-id=\"4d32c080\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>\u00a0 \u00a0 \u00a0 \u00a0\u0e43\u0e19\u0e1a\u0e23\u0e23\u0e14\u0e32\u0e22\u0e32\u0e23\u0e31\u0e01\u0e29\u0e32\u0e21\u0e30\u0e40\u0e23\u0e47\u0e07\u0e41\u0e1a\u0e1a\u0e21\u0e38\u0e48\u0e07\u0e40\u0e1b\u0e49\u0e32 \u0e22\u0e32\u0e43\u0e19\u0e01\u0e25\u0e38\u0e48\u0e21 <\/strong><strong>\u2018sorafenib\u2019 \u0e40\u0e1b\u0e47\u0e19\u0e2b\u0e19\u0e36\u0e48\u0e07\u0e43\u0e19\u0e22\u0e32\u0e17\u0e35\u0e48\u0e43\u0e2b\u0e49\u0e1c\u0e25\u0e01\u0e32\u0e23\u0e23\u0e31\u0e01\u0e29\u0e32\u0e17\u0e35\u0e48\u0e19\u0e48\u0e32\u0e1e\u0e2d\u0e43\u0e08\u0e43\u0e19\u0e1c\u0e39\u0e49\u0e1b\u0e48\u0e27\u0e22 \u0e41\u0e15\u0e48\u0e1c\u0e25\u0e02\u0e2d\u0e07\u0e22\u0e32\u0e04\u0e07\u0e2d\u0e22\u0e39\u0e48\u0e44\u0e14\u0e49\u0e44\u0e21\u0e48\u0e19\u0e32\u0e19\u0e40\u0e19\u0e37\u0e48\u0e2d\u0e07\u0e08\u0e32\u0e01\u0e40\u0e01\u0e34\u0e14\u0e01\u0e32\u0e23\u0e14\u0e37\u0e49\u0e2d\u0e15\u0e48\u0e2d\u0e22\u0e32<\/strong> \u0e07\u0e32\u0e19\u0e27\u0e34\u0e08\u0e31\u0e22\u0e19\u0e35\u0e49\u0e40\u0e23\u0e32\u0e43\u0e0a\u0e49\u0e40\u0e17\u0e04\u0e19\u0e34\u0e04 <strong>genome-wide CRISPR knock out screen<\/strong> \u0e0b\u0e36\u0e48\u0e07\u0e40\u0e1b\u0e47\u0e19\u0e40\u0e17\u0e04\u0e19\u0e34\u0e04\u0e17\u0e35\u0e48\u0e2a\u0e32\u0e21\u0e32\u0e23\u0e16\u0e23\u0e30\u0e1a\u0e38\u0e27\u0e48\u0e32\u0e22\u0e35\u0e19\u0e43\u0e14\u0e02\u0e2d\u0e07\u0e21\u0e19\u0e38\u0e29\u0e22\u0e4c\u0e40\u0e01\u0e35\u0e48\u0e22\u0e27\u0e02\u0e49\u0e2d\u0e07\u0e01\u0e31\u0e1a\u0e01\u0e32\u0e23\u0e15\u0e2d\u0e1a\u0e2a\u0e19\u0e2d\u0e07\u0e15\u0e48\u0e2d\u0e22\u0e32\u0e01\u0e25\u0e38\u0e48\u0e21\u0e19\u0e35\u0e49\u0e44\u0e14\u0e49 <strong>\u0e40\u0e1e\u0e37\u0e48\u0e2d\u0e17\u0e35\u0e48\u0e08\u0e30\u0e17\u0e33\u0e04\u0e27\u0e32\u0e21\u0e40\u0e02\u0e49\u0e32\u0e43\u0e08\u0e27\u0e48\u0e32\u0e1c\u0e39\u0e49\u0e1b\u0e48\u0e27\u0e22\u0e40\u0e01\u0e34\u0e14\u0e01\u0e32\u0e23\u0e14\u0e37\u0e49\u0e2d\u0e15\u0e48\u0e2d\u0e22\u0e32\u0e44\u0e14\u0e49\u0e2d\u0e22\u0e48\u0e32\u0e07\u0e44\u0e23<\/strong><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-51636127 elementor-widget elementor-widget-text-editor\" data-id=\"51636127\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>\u00a0 \u00a0 \u00a0 \u00a0\u0e40\u0e23\u0e32\u0e1e\u0e1a\u0e27\u0e48\u0e32<strong>\u0e22\u0e35\u0e19\u0e2b\u0e25\u0e32\u0e22\u0e15\u0e31\u0e27\u0e17\u0e35\u0e48\u0e17\u0e33\u0e2b\u0e19\u0e49\u0e32\u0e17\u0e35\u0e48\u0e22\u0e31\u0e1a\u0e22\u0e31\u0e49\u0e07\u0e01\u0e32\u0e23\u0e17\u0e33\u0e07\u0e32\u0e19\u0e02\u0e2d\u0e07 <\/strong><strong>MAPK pathways<\/strong><strong> \u0e0b\u0e36\u0e48\u0e07\u0e40\u0e1b\u0e47\u0e19\u0e27\u0e34\u0e16\u0e35\u0e01\u0e32\u0e23\u0e2a\u0e48\u0e07\u0e2a\u0e31\u0e0d\u0e0d\u0e32\u0e13\u0e20\u0e32\u0e22\u0e43\u0e19\u0e40\u0e0b\u0e25\u0e25\u0e4c\u0e17\u0e35\u0e48\u0e01\u0e23\u0e30\u0e15\u0e38\u0e49\u0e19\u0e01\u0e32\u0e23\u0e40\u0e08\u0e23\u0e34\u0e0d\u0e02\u0e2d\u0e07\u0e21\u0e30\u0e40\u0e23\u0e47\u0e07 \u0e41\u0e25\u0e30 MTOR pathways \u0e17\u0e35\u0e48\u0e21\u0e35\u0e1a\u0e17\u0e1a\u0e32\u0e17\u0e43\u0e19\u0e01\u0e32\u0e23\u0e04\u0e27\u0e1a\u0e04\u0e38\u0e21\u0e01\u0e34\u0e08\u0e01\u0e23\u0e23\u0e21\u0e15\u0e48\u0e32\u0e07 \u0e46 \u0e43\u0e19\u0e40\u0e0b\u0e25\u0e25\u0e4c \u0e40\u0e21\u0e37\u0e48\u0e2d\u0e16\u0e39\u0e01\u0e17\u0e33\u0e43\u0e2b\u0e49\u0e44\u0e21\u0e48\u0e17\u0e33\u0e07\u0e32\u0e19\u0e08\u0e30\u0e17\u0e33\u0e43\u0e2b\u0e49\u0e40\u0e0b\u0e25\u0e25\u0e4c\u0e21\u0e30\u0e40\u0e23\u0e47\u0e07\u0e14\u0e37\u0e49\u0e2d\u0e22\u0e32\u0e21\u0e32\u0e01\u0e02\u0e36\u0e49\u0e19<\/strong> \u0e08\u0e36\u0e07\u0e44\u0e14\u0e49\u0e17\u0e33\u0e01\u0e32\u0e23\u0e28\u0e36\u0e01\u0e29\u0e32\u0e22\u0e37\u0e19\u0e22\u0e31\u0e19\u0e1c\u0e25\u0e02\u0e2d\u0e07\u0e22\u0e35\u0e19\u0e40\u0e2b\u0e25\u0e48\u0e32\u0e19\u0e35\u0e49\u0e17\u0e35\u0e25\u0e30\u0e15\u0e31\u0e27 \u0e41\u0e25\u0e30\u0e1e\u0e1a\u0e1c\u0e25\u0e17\u0e35\u0e48\u0e2a\u0e2d\u0e14\u0e04\u0e25\u0e49\u0e2d\u0e07\u0e01\u0e31\u0e19\u0e27\u0e48\u0e32<strong>\u0e1c\u0e39\u0e49\u0e1b\u0e48\u0e27\u0e22\u0e17\u0e35\u0e48\u0e21\u0e35\u0e1b\u0e23\u0e34\u0e21\u0e32\u0e13\u0e02\u0e2d\u0e07\u0e1c\u0e25\u0e1c\u0e25\u0e34\u0e15\u0e08\u0e32\u0e01\u0e22\u0e35\u0e19\u0e40\u0e2b\u0e25\u0e48\u0e32\u0e19\u0e35\u0e49\u0e15\u0e48\u0e33\u0e08\u0e30\u0e15\u0e2d\u0e1a\u0e2a\u0e19\u0e2d\u0e07\u0e15\u0e48\u0e2d\u0e22\u0e32\u0e44\u0e21\u0e48\u0e14\u0e35<\/strong><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c7db2d3 elementor-widget elementor-widget-text-editor\" data-id=\"c7db2d3\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>\u00a0 \u00a0 \u00a0 \u00a0\u0e19\u0e2d\u0e01\u0e08\u0e32\u0e01\u0e19\u0e31\u0e49\u0e19\u0e40\u0e23\u0e32\u0e44\u0e14\u0e49\u0e2a\u0e23\u0e49\u0e32\u0e07\u0e40\u0e0b\u0e25\u0e25\u0e4c\u0e21\u0e30\u0e40\u0e23\u0e47\u0e07\u0e17\u0e35\u0e48\u0e14\u0e37\u0e49\u0e2d\u0e15\u0e48\u0e2d\u0e22\u0e32 sorafenib \u0e41\u0e25\u0e30\u0e1e\u0e1a\u0e27\u0e48\u0e32\u0e40\u0e0b\u0e25\u0e25\u0e4c\u0e40\u0e2b\u0e25\u0e48\u0e32\u0e19\u0e35\u0e49\u0e21\u0e35\u0e01\u0e32\u0e23\u0e17\u0e33\u0e07\u0e32\u0e19\u0e02\u0e2d\u0e07 MAPK \u0e41\u0e25\u0e30 MTOR pathways \u0e2a\u0e39\u0e07\u00a0<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1b2ec0bc elementor-widget elementor-widget-qi_addons_for_elementor_blockquote\" data-id=\"1b2ec0bc\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"qi_addons_for_elementor_blockquote.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"qodef-shortcode qodef-m qodef-qi-blockquote qodef-layout--top qodef--icon-pack\">\n\t\t\t<div class=\"qodef-m-icon\">\n\t\t\t<i aria-hidden=\"true\" class=\"fas fa-quote-right\"><\/i>\t\t<\/div>\n\t\t\t\t<p class=\"qodef-m-text\">\n\t\t\t\u0e14\u0e31\u0e07\u0e19\u0e31\u0e49\u0e19\u0e01\u0e32\u0e23\u0e43\u0e0a\u0e49\u0e22\u0e32\u0e22\u0e31\u0e1a\u0e22\u0e31\u0e49\u0e07\u0e01\u0e32\u0e23\u0e17\u0e33\u0e07\u0e32\u0e19\u0e02\u0e2d\u0e07 MAPK signaling \u0e23\u0e48\u0e27\u0e21\u0e01\u0e31\u0e1a\u0e22\u0e32\u0e22\u0e31\u0e1a\u0e22\u0e31\u0e49\u0e07 FLT3 \u0e08\u0e30\u0e2a\u0e32\u0e21\u0e32\u0e23\u0e16\u0e08\u0e31\u0e14\u0e01\u0e32\u0e23\u0e01\u0e31\u0e1a\u0e40\u0e0b\u0e25\u0e25\u0e4c\u0e21\u0e30\u0e40\u0e23\u0e47\u0e07\u0e44\u0e14\u0e49\u0e14\u0e35\u0e01\u0e27\u0e48\u0e32\t\t<\/p>\n\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-180e2c10 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"180e2c10\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-cdda223 e-con-full e-flex e-con e-child\" data-id=\"cdda223\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-11e932a5 elementor-widget elementor-widget-qi_addons_for_elementor_button\" data-id=\"11e932a5\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"qi_addons_for_elementor_button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<a class=\"qodef-shortcode qodef-m qodef-qi-button qodef-html--link qodef-layout--filled qodef-type--standard qodef-size--small qodef-icon--right qodef-hover--icon-move-horizontal-short\" href=\"https:\/\/haematologica.org\/article\/view\/haematol.2020.257964\" target=\"_self\">\n\t<span class=\"qodef-m-text\">\u0e02\u0e49\u0e2d\u0e21\u0e39\u0e25\u0e40\u0e1e\u0e34\u0e48\u0e21\u0e40\u0e15\u0e34\u0e21<\/span>\n\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-2e9e284b e-flex e-con-boxed e-con e-parent\" data-id=\"2e9e284b\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-5747e041 e-con-full e-flex e-con e-child\" data-id=\"5747e041\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-74db3314 elementor-widget elementor-widget-heading\" data-id=\"74db3314\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h5 class=\"elementor-heading-title elementor-size-default\">SDGs \u0e2b\u0e25\u0e31\u0e01<\/h5>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-763a2d8b e-con-full e-flex e-con e-child\" data-id=\"763a2d8b\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-16c28a39 elementor-widget__width-initial elementor-widget elementor-widget-image\" data-id=\"16c28a39\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"300\" src=\"https:\/\/science.mahidol.ac.th\/simple-science\/wp-content\/uploads\/2023\/05\/E-WEB-Goal-03-300x300.png\" class=\"attachment-medium size-medium wp-image-9199\" alt=\"\" srcset=\"https:\/\/science.mahidol.ac.th\/simple-science\/wp-content\/uploads\/2023\/05\/E-WEB-Goal-03-300x300.png 300w, https:\/\/science.mahidol.ac.th\/simple-science\/wp-content\/uploads\/2023\/05\/E-WEB-Goal-03-150x150.png 150w, https:\/\/science.mahidol.ac.th\/simple-science\/wp-content\/uploads\/2023\/05\/E-WEB-Goal-03-768x768.png 768w, https:\/\/science.mahidol.ac.th\/simple-science\/wp-content\/uploads\/2023\/05\/E-WEB-Goal-03-570x570.png 570w, https:\/\/science.mahidol.ac.th\/simple-science\/wp-content\/uploads\/2023\/05\/E-WEB-Goal-03-500x500.png 500w, https:\/\/science.mahidol.ac.th\/simple-science\/wp-content\/uploads\/2023\/05\/E-WEB-Goal-03-1000x1000.png 1000w, https:\/\/science.mahidol.ac.th\/simple-science\/wp-content\/uploads\/2023\/05\/E-WEB-Goal-03-700x700.png 700w, https:\/\/science.mahidol.ac.th\/simple-science\/wp-content\/uploads\/2023\/05\/E-WEB-Goal-03-650x650.png 650w, https:\/\/science.mahidol.ac.th\/simple-science\/wp-content\/uploads\/2023\/05\/E-WEB-Goal-03-1300x1300.png 1300w, https:\/\/science.mahidol.ac.th\/simple-science\/wp-content\/uploads\/2023\/05\/E-WEB-Goal-03.png 1500w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-18aa365 elementor-widget elementor-widget-text-editor\" data-id=\"18aa365\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\u0e2a\u0e23\u0e49\u0e32\u0e07\u0e2b\u0e25\u0e31\u0e01\u0e1b\u0e23\u0e30\u0e01\u0e31\u0e19\u0e27\u0e48\u0e32\u0e04\u0e19\u0e21\u0e35\u0e0a\u0e35\u0e27\u0e34\u0e15\u0e17\u0e35\u0e48\u0e21\u0e35\u0e2a\u0e38\u0e02\u0e20\u0e32\u0e1e\u0e14\u0e35\u0e41\u0e25\u0e30\u0e2a\u0e48\u0e07\u0e40\u0e2a\u0e23\u0e34\u0e21\u0e2a\u0e27\u0e31\u0e2a\u0e14\u0e34\u0e20\u0e32\u0e1e\u0e2a\u0e33\u0e2b\u0e23\u0e31\u0e1a\u0e17\u0e38\u0e01\u0e04\u0e19\u0e43\u0e19\u0e17\u0e38\u0e01\u0e27\u0e31\u0e22\n(Ensure healthy lives and promote well-being for all at all ages)\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-3bb0270f e-flex e-con-boxed e-con e-parent\" data-id=\"3bb0270f\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-7b7cbe0d e-con-full e-flex e-con e-child\" data-id=\"7b7cbe0d\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-1286d26c elementor-widget-divider--view-line_text elementor-widget-divider--element-align-left elementor-widget elementor-widget-divider\" data-id=\"1286d26c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t\t<span class=\"elementor-divider__text elementor-divider__element\">\n\t\t\t\t\u0e1a\u0e17\u0e04\u0e27\u0e32\u0e21\u0e2d\u0e37\u0e48\u0e19 \u0e46 \u0e17\u0e35\u0e48\u0e19\u0e48\u0e32\u0e2a\u0e19\u0e43\u0e08\t\t\t\t<\/span>\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-6654d491 e-con-full e-flex e-con e-child\" data-id=\"6654d491\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-3c63765d qodef-navigation-together--bottom elementor-widget elementor-widget-qi_addons_for_elementor_blog_slider\" data-id=\"3c63765d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"qi_addons_for_elementor_blog_slider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"qodef-shortcode qodef-m qodef-addons-blog-slider qodef-item-layout--boxed qodef-info-no-icons qodef-image--hover-zoom qodef-qi-grid qodef-qi-swiper-container qodef-item-layout--boxed qodef-navigation--together qodef-navigation-alignment--flex-end qodef-pagination--inside qodef-navigation--hover-move\" data-options=\"{&quot;direction&quot;:&quot;horizontal&quot;,&quot;slidesPerView&quot;:&quot;3&quot;,&quot;spaceBetween&quot;:12,&quot;spaceBetweenTablet&quot;:30,&quot;spaceBetweenMobile&quot;:30,&quot;effect&quot;:&quot;&quot;,&quot;loop&quot;:false,&quot;autoplay&quot;:false,&quot;centeredSlides&quot;:false,&quot;speed&quot;:&quot;&quot;,&quot;speedAnimation&quot;:&quot;&quot;,&quot;outsideNavigation&quot;:&quot;yes&quot;,&quot;outsidePagination&quot;:&quot;no&quot;,&quot;unique&quot;:&quot;1&quot;,&quot;partialValue&quot;:0,&quot;disablePartialValue&quot;:&quot;&quot;,&quot;parallax&quot;:&quot;no&quot;}\">\n\t<div class=\"swiper-wrapper\">\n\t\t<article class=\"qodef-e qodef-blog-item swiper-slide qodef-item--full post-16935 post type-post status-publish format-standard has-post-thumbnail hentry category-pls category-articles tag-1708 tag-1709\">\n\t<div class=\"qodef-e-inner\">\n\t\t<div class=\"qodef-e-media-holder\">\n\t\t\t<div class=\"qodef-e-media\">\n\t\t<div class=\"qodef-e-media-image\">\n\t\t<a itemprop=\"url\" href=\"https:\/\/science.mahidol.ac.th\/simple-science\/2024\/09\/06\/sep67-03\/\">\n\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"3750\" height=\"1963\" src=\"https:\/\/science.mahidol.ac.th\/simple-science\/wp-content\/uploads\/2024\/09\/Simple-Science-1.png\" class=\"attachment-full size-full\" alt=\"\" srcset=\"https:\/\/science.mahidol.ac.th\/simple-science\/wp-content\/uploads\/2024\/09\/Simple-Science-1.png 3750w, https:\/\/science.mahidol.ac.th\/simple-science\/wp-content\/uploads\/2024\/09\/Simple-Science-1-300x157.png 300w, https:\/\/science.mahidol.ac.th\/simple-science\/wp-content\/uploads\/2024\/09\/Simple-Science-1-768x402.png 768w, https:\/\/science.mahidol.ac.th\/simple-science\/wp-content\/uploads\/2024\/09\/Simple-Science-1-1536x804.png 1536w, https:\/\/science.mahidol.ac.th\/simple-science\/wp-content\/uploads\/2024\/09\/Simple-Science-1-2048x1072.png 2048w, https:\/\/science.mahidol.ac.th\/simple-science\/wp-content\/uploads\/2024\/09\/Simple-Science-1-700x366.png 700w\" sizes=\"(max-width: 3750px) 100vw, 3750px\" \/>\t\t<\/a>\n\t\t\t<\/div>\n<\/div>\n\t\t<\/div>\n\t\t<div class=\"qodef-e-content\">\n\t\t\t\t\t\t\t<div class=\"qodef-e-info qodef-info--top\">\n\t\t\t\t\t<div class=\"qodef-e-info-item qodef-e-info-category\">\n\t\t<a href=\"https:\/\/science.mahidol.ac.th\/simple-science\/category\/pls\/\" rel=\"category tag\">PLS<\/a><span class=\"qodef-category-separator\"><\/span><a href=\"https:\/\/science.mahidol.ac.th\/simple-science\/category\/articles\/\" rel=\"category tag\">\u0e1a\u0e17\u0e04\u0e27\u0e32\u0e21<\/a><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<div class=\"qodef-e-text\">\n\t\t\t\t<h5 itemprop=\"name\" class=\"qodef-e-title entry-title\">\n\t<a itemprop=\"url\" class=\"qodef-e-title-link\" href=\"https:\/\/science.mahidol.ac.th\/simple-science\/2024\/09\/06\/sep67-03\/\">\n\t\t\u0e2a\u0e48\u0e2d\u0e07\u0e1e\u0e38\u0e48\u0e21\u0e17\u0e38\u0e40\u0e23\u0e35\u0e22\u0e19\u0e43\u0e19\u0e27\u0e34\u0e21\u0e32\u0e19\u0e2b\u0e19\u0e32\u0e21\t<\/a>\n<\/h5>\n\t\t<p itemprop=\"description\" class=\"qodef-e-excerpt\">\n\t\t\t\t\t<\/p>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t<\/div>\n<\/article>\n<article class=\"qodef-e qodef-blog-item swiper-slide qodef-item--full post-16171 post type-post status-publish format-standard has-post-thumbnail hentry category-pls category-articles tag-1683 tag-1681 tag-1678 tag-142\">\n\t<div class=\"qodef-e-inner\">\n\t\t<div class=\"qodef-e-media-holder\">\n\t\t\t<div class=\"qodef-e-media\">\n\t\t<div class=\"qodef-e-media-image\">\n\t\t<a itemprop=\"url\" href=\"https:\/\/science.mahidol.ac.th\/simple-science\/2024\/04\/26\/pls-292\/\">\n\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"5000\" height=\"2617\" src=\"https:\/\/science.mahidol.ac.th\/simple-science\/wp-content\/uploads\/2024\/04\/Simple-Science-1.png\" class=\"attachment-full size-full\" alt=\"\" srcset=\"https:\/\/science.mahidol.ac.th\/simple-science\/wp-content\/uploads\/2024\/04\/Simple-Science-1.png 5000w, https:\/\/science.mahidol.ac.th\/simple-science\/wp-content\/uploads\/2024\/04\/Simple-Science-1-300x157.png 300w, https:\/\/science.mahidol.ac.th\/simple-science\/wp-content\/uploads\/2024\/04\/Simple-Science-1-768x402.png 768w, https:\/\/science.mahidol.ac.th\/simple-science\/wp-content\/uploads\/2024\/04\/Simple-Science-1-1536x804.png 1536w, https:\/\/science.mahidol.ac.th\/simple-science\/wp-content\/uploads\/2024\/04\/Simple-Science-1-2048x1072.png 2048w, https:\/\/science.mahidol.ac.th\/simple-science\/wp-content\/uploads\/2024\/04\/Simple-Science-1-700x366.png 700w\" sizes=\"(max-width: 5000px) 100vw, 5000px\" \/>\t\t<\/a>\n\t\t\t<\/div>\n<\/div>\n\t\t<\/div>\n\t\t<div class=\"qodef-e-content\">\n\t\t\t\t\t\t\t<div class=\"qodef-e-info qodef-info--top\">\n\t\t\t\t\t<div class=\"qodef-e-info-item qodef-e-info-category\">\n\t\t<a href=\"https:\/\/science.mahidol.ac.th\/simple-science\/category\/pls\/\" rel=\"category tag\">PLS<\/a><span class=\"qodef-category-separator\"><\/span><a href=\"https:\/\/science.mahidol.ac.th\/simple-science\/category\/articles\/\" rel=\"category tag\">\u0e1a\u0e17\u0e04\u0e27\u0e32\u0e21<\/a><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<div class=\"qodef-e-text\">\n\t\t\t\t<h5 itemprop=\"name\" class=\"qodef-e-title entry-title\">\n\t<a itemprop=\"url\" class=\"qodef-e-title-link\" href=\"https:\/\/science.mahidol.ac.th\/simple-science\/2024\/04\/26\/pls-292\/\">\n\t\t\u0e15\u0e2d\u0e1a\u0e42\u0e08\u0e17\u0e22\u0e4c\u0e04\u0e27\u0e32\u0e21\u0e22\u0e31\u0e48\u0e07\u0e22\u0e37\u0e19 \u0e0b\u0e31\u0e25\u0e42\u0e1f\u0e40\u0e25\u0e19 \u0e15\u0e31\u0e27\u0e17\u0e33\u0e25\u0e30\u0e25\u0e32\u0e22 \u0e40\u0e2a\u0e23\u0e34\u0e21\u0e1b\u0e23\u0e30\u0e2a\u0e34\u0e17\u0e18\u0e34\u0e20\u0e32\u0e1e\u0e43\u0e2b\u0e49\u0e40\u0e0b\u0e25\u0e25\u0e4c\u0e41\u0e2a\u0e07\u0e2d\u0e32\u0e17\u0e34\u0e15\u0e22\u0e4c\t<\/a>\n<\/h5>\n\t\t<p itemprop=\"description\" class=\"qodef-e-excerpt\">\n\t\t\t\t\t<\/p>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t<\/div>\n<\/article>\n<article class=\"qodef-e qodef-blog-item swiper-slide qodef-item--full post-16018 post type-post status-publish format-standard has-post-thumbnail hentry category-pls category-articles tag-1676 tag-1666 tag-1664 tag-1667 tag-1671\">\n\t<div class=\"qodef-e-inner\">\n\t\t<div class=\"qodef-e-media-holder\">\n\t\t\t<div class=\"qodef-e-media\">\n\t\t<div class=\"qodef-e-media-image\">\n\t\t<a itemprop=\"url\" href=\"https:\/\/science.mahidol.ac.th\/simple-science\/2024\/04\/19\/pls-286\/\">\n\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"7500\" height=\"3926\" src=\"https:\/\/science.mahidol.ac.th\/simple-science\/wp-content\/uploads\/2024\/04\/Simple-Science-.png\" class=\"attachment-full size-full\" alt=\"\" srcset=\"https:\/\/science.mahidol.ac.th\/simple-science\/wp-content\/uploads\/2024\/04\/Simple-Science-.png 7500w, https:\/\/science.mahidol.ac.th\/simple-science\/wp-content\/uploads\/2024\/04\/Simple-Science--300x157.png 300w, https:\/\/science.mahidol.ac.th\/simple-science\/wp-content\/uploads\/2024\/04\/Simple-Science--768x402.png 768w, https:\/\/science.mahidol.ac.th\/simple-science\/wp-content\/uploads\/2024\/04\/Simple-Science--1536x804.png 1536w, https:\/\/science.mahidol.ac.th\/simple-science\/wp-content\/uploads\/2024\/04\/Simple-Science--2048x1072.png 2048w, https:\/\/science.mahidol.ac.th\/simple-science\/wp-content\/uploads\/2024\/04\/Simple-Science--700x366.png 700w\" sizes=\"(max-width: 7500px) 100vw, 7500px\" \/>\t\t<\/a>\n\t\t\t<\/div>\n<\/div>\n\t\t<\/div>\n\t\t<div class=\"qodef-e-content\">\n\t\t\t\t\t\t\t<div class=\"qodef-e-info qodef-info--top\">\n\t\t\t\t\t<div class=\"qodef-e-info-item qodef-e-info-category\">\n\t\t<a href=\"https:\/\/science.mahidol.ac.th\/simple-science\/category\/pls\/\" rel=\"category tag\">PLS<\/a><span class=\"qodef-category-separator\"><\/span><a href=\"https:\/\/science.mahidol.ac.th\/simple-science\/category\/articles\/\" rel=\"category tag\">\u0e1a\u0e17\u0e04\u0e27\u0e32\u0e21<\/a><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<div class=\"qodef-e-text\">\n\t\t\t\t<h5 itemprop=\"name\" class=\"qodef-e-title entry-title\">\n\t<a itemprop=\"url\" class=\"qodef-e-title-link\" href=\"https:\/\/science.mahidol.ac.th\/simple-science\/2024\/04\/19\/pls-286\/\">\n\t\t\u0e27\u0e31\u0e2a\u0e14\u0e38\u0e14\u0e39\u0e14\u0e0b\u0e31\u0e1a \u0e2a\u0e38\u0e14\u0e17\u0e23\u0e07\u0e1e\u0e25\u0e31\u0e07 \u0e41\u0e01\u0e23\u0e1f\u0e35\u0e19\u0e2d\u0e2d\u0e01\u0e44\u0e0b\u0e14\u0e4c \u0e40\u0e04\u0e25\u0e37\u0e2d\u0e1a\u0e44\u0e17\u0e40\u0e17\u0e40\u0e19\u0e35\u0e22 \u0e15\u0e31\u0e27\u0e0a\u0e48\u0e27\u0e22\u0e41\u0e2b\u0e48\u0e07\u0e2d\u0e19\u0e32\u0e04\u0e15 \u0e1e\u0e23\u0e49\u0e2d\u0e21\u0e02\u0e08\u0e31\u0e14\u0e44\u0e2d\u0e2d\u0e2d\u0e19\u0e1f\u0e2d\u0e2a\u0e40\u0e1f\u0e15 \u0e43\u0e19\u0e19\u0e49\u0e33\u0e40\u0e2a\u0e35\u0e22\t<\/a>\n<\/h5>\n\t\t<p itemprop=\"description\" class=\"qodef-e-excerpt\">\n\t\t\t\t\t<\/p>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t<\/div>\n<\/article>\n<article class=\"qodef-e qodef-blog-item swiper-slide qodef-item--full post-15853 post type-post status-publish format-standard has-post-thumbnail hentry category-pls category-articles tag-covid-19 tag-sars-cov-2 tag-1661 tag-1654 tag---2\">\n\t<div class=\"qodef-e-inner\">\n\t\t<div class=\"qodef-e-media-holder\">\n\t\t\t<div class=\"qodef-e-media\">\n\t\t<div class=\"qodef-e-media-image\">\n\t\t<a itemprop=\"url\" href=\"https:\/\/science.mahidol.ac.th\/simple-science\/2024\/04\/05\/pls-268\/\">\n\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"5000\" height=\"2617\" src=\"https:\/\/science.mahidol.ac.th\/simple-science\/wp-content\/uploads\/2024\/04\/Simple-Science-1-1.png\" class=\"attachment-full size-full\" alt=\"\" srcset=\"https:\/\/science.mahidol.ac.th\/simple-science\/wp-content\/uploads\/2024\/04\/Simple-Science-1-1.png 5000w, https:\/\/science.mahidol.ac.th\/simple-science\/wp-content\/uploads\/2024\/04\/Simple-Science-1-1-300x157.png 300w, https:\/\/science.mahidol.ac.th\/simple-science\/wp-content\/uploads\/2024\/04\/Simple-Science-1-1-768x402.png 768w, https:\/\/science.mahidol.ac.th\/simple-science\/wp-content\/uploads\/2024\/04\/Simple-Science-1-1-1536x804.png 1536w, https:\/\/science.mahidol.ac.th\/simple-science\/wp-content\/uploads\/2024\/04\/Simple-Science-1-1-2048x1072.png 2048w, https:\/\/science.mahidol.ac.th\/simple-science\/wp-content\/uploads\/2024\/04\/Simple-Science-1-1-700x366.png 700w\" sizes=\"(max-width: 5000px) 100vw, 5000px\" \/>\t\t<\/a>\n\t\t\t<\/div>\n<\/div>\n\t\t<\/div>\n\t\t<div class=\"qodef-e-content\">\n\t\t\t\t\t\t\t<div class=\"qodef-e-info qodef-info--top\">\n\t\t\t\t\t<div class=\"qodef-e-info-item qodef-e-info-category\">\n\t\t<a href=\"https:\/\/science.mahidol.ac.th\/simple-science\/category\/pls\/\" rel=\"category tag\">PLS<\/a><span class=\"qodef-category-separator\"><\/span><a href=\"https:\/\/science.mahidol.ac.th\/simple-science\/category\/articles\/\" rel=\"category tag\">\u0e1a\u0e17\u0e04\u0e27\u0e32\u0e21<\/a><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<div class=\"qodef-e-text\">\n\t\t\t\t<h5 itemprop=\"name\" class=\"qodef-e-title entry-title\">\n\t<a itemprop=\"url\" class=\"qodef-e-title-link\" href=\"https:\/\/science.mahidol.ac.th\/simple-science\/2024\/04\/05\/pls-268\/\">\n\t\t\u0e1e\u0e27\u0e01\u0e21\u0e31\u0e19\u0e1b\u0e23\u0e31\u0e1a\u0e15\u0e31\u0e27 \u0e40\u0e1e\u0e37\u0e48\u0e2d\u0e04\u0e27\u0e32\u0e21\u0e2d\u0e22\u0e39\u0e48\u0e23\u0e2d\u0e14!! SARS-CoV-2 \u0e02\u0e22\u0e32\u0e22\u0e1e\u0e31\u0e19\u0e18\u0e38\u0e4c\u0e1e\u0e23\u0e49\u0e2d\u0e21\u0e1b\u0e23\u0e31\u0e1a\u0e15\u0e31\u0e27 \u0e19\u0e31\u0e01\u0e27\u0e34\u0e08\u0e31\u0e22\u0e40\u0e1d\u0e49\u0e32\u0e08\u0e31\u0e1a\u0e15\u0e32\u0e2d\u0e22\u0e48\u0e32\u0e07\u0e43\u0e01\u0e25\u0e49\u0e0a\u0e34\u0e14\t<\/a>\n<\/h5>\n\t\t<p itemprop=\"description\" class=\"qodef-e-excerpt\">\n\t\t\t\t\t<\/p>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t<\/div>\n<\/article>\n<article class=\"qodef-e qodef-blog-item swiper-slide qodef-item--full post-15781 post type-post status-publish format-standard has-post-thumbnail hentry category-pls category-articles tag-cu-chitosan tag-1644 tag-1647 tag-1638 tag-1628\">\n\t<div class=\"qodef-e-inner\">\n\t\t<div class=\"qodef-e-media-holder\">\n\t\t\t<div class=\"qodef-e-media\">\n\t\t<div class=\"qodef-e-media-image\">\n\t\t<a itemprop=\"url\" href=\"https:\/\/science.mahidol.ac.th\/simple-science\/2024\/03\/28\/pls-261\/\">\n\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"5000\" height=\"2617\" src=\"https:\/\/science.mahidol.ac.th\/simple-science\/wp-content\/uploads\/2024\/03\/Simple-Science-1-2.png\" class=\"attachment-full size-full\" alt=\"\" srcset=\"https:\/\/science.mahidol.ac.th\/simple-science\/wp-content\/uploads\/2024\/03\/Simple-Science-1-2.png 5000w, https:\/\/science.mahidol.ac.th\/simple-science\/wp-content\/uploads\/2024\/03\/Simple-Science-1-2-300x157.png 300w, https:\/\/science.mahidol.ac.th\/simple-science\/wp-content\/uploads\/2024\/03\/Simple-Science-1-2-768x402.png 768w, https:\/\/science.mahidol.ac.th\/simple-science\/wp-content\/uploads\/2024\/03\/Simple-Science-1-2-1536x804.png 1536w, https:\/\/science.mahidol.ac.th\/simple-science\/wp-content\/uploads\/2024\/03\/Simple-Science-1-2-2048x1072.png 2048w, https:\/\/science.mahidol.ac.th\/simple-science\/wp-content\/uploads\/2024\/03\/Simple-Science-1-2-700x366.png 700w\" sizes=\"(max-width: 5000px) 100vw, 5000px\" \/>\t\t<\/a>\n\t\t\t<\/div>\n<\/div>\n\t\t<\/div>\n\t\t<div class=\"qodef-e-content\">\n\t\t\t\t\t\t\t<div class=\"qodef-e-info qodef-info--top\">\n\t\t\t\t\t<div class=\"qodef-e-info-item qodef-e-info-category\">\n\t\t<a href=\"https:\/\/science.mahidol.ac.th\/simple-science\/category\/pls\/\" rel=\"category tag\">PLS<\/a><span class=\"qodef-category-separator\"><\/span><a href=\"https:\/\/science.mahidol.ac.th\/simple-science\/category\/articles\/\" rel=\"category tag\">\u0e1a\u0e17\u0e04\u0e27\u0e32\u0e21<\/a><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<div class=\"qodef-e-text\">\n\t\t\t\t<h5 itemprop=\"name\" class=\"qodef-e-title entry-title\">\n\t<a itemprop=\"url\" class=\"qodef-e-title-link\" href=\"https:\/\/science.mahidol.ac.th\/simple-science\/2024\/03\/28\/pls-261\/\">\n\t\t\u0e1b\u0e23\u0e30\u0e08\u0e31\u0e01\u0e29\u0e4c\u0e2a\u0e39\u0e48\u0e2a\u0e32\u0e22\u0e15\u0e32\u0e42\u0e25\u0e01 \u0e40\u0e21\u0e47\u0e14\u0e1a\u0e35\u0e14 \u0e15\u0e31\u0e27\u0e40\u0e23\u0e48\u0e07\u0e1b\u0e0f\u0e34\u0e01\u0e34\u0e23\u0e34\u0e22\u0e32\u0e1b\u0e23\u0e30\u0e2a\u0e34\u0e17\u0e18\u0e34\u0e20\u0e32\u0e1e\u0e2a\u0e39\u0e07 \u0e15\u0e2d\u0e1a\u0e42\u0e08\u0e17\u0e22\u0e4c\u0e04\u0e27\u0e32\u0e21\u0e22\u0e31\u0e48\u0e07\u0e22\u0e37\u0e19\u0e43\u0e2b\u0e49\u0e41\u0e01\u0e48\u0e42\u0e25\u0e01\t<\/a>\n<\/h5>\n\t\t<p itemprop=\"description\" class=\"qodef-e-excerpt\">\n\t\t\t\t\t<\/p>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t<\/div>\n<\/article>\n\t<\/div>\n\t\t<div class=\"swiper-pagination\"><\/div>\n<\/div>\n\t\t\t<div class=\"qodef-swiper-together-nav\">\n\t\t\t<div class=\"qodef-swiper-together-inner\">\n\t\t<div class=\"swiper-button-prev swiper-button-outside swiper-button-prev-1\"><svg class=\"qodef-swiper-arrow-left\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" x=\"0px\" y=\"0px\" viewBox=\"0 0 34.2 32.3\" xml:space=\"preserve\" style=\"stroke-width: 2;\"><line x1=\"0.5\" y1=\"16\" x2=\"33.5\" y2=\"16\"\/><line x1=\"0.3\" y1=\"16.5\" x2=\"16.2\" y2=\"0.7\"\/><line x1=\"0\" y1=\"15.4\" x2=\"16.2\" y2=\"31.6\"\/><\/svg><\/div>\n\t<div class=\"swiper-button-next swiper-button-outside swiper-button-next-1\"><svg class=\"qodef-swiper-arrow-right\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" x=\"0px\" y=\"0px\" viewBox=\"0 0 34.2 32.3\" xml:space=\"preserve\" style=\"stroke-width: 2;\"><line x1=\"0\" y1=\"16\" x2=\"33\" y2=\"16\"\/><line x1=\"17.3\" y1=\"0.7\" x2=\"33.2\" y2=\"16.5\"\/><line x1=\"17.3\" y1=\"31.6\" x2=\"33.5\" y2=\"15.4\"\/><\/svg><\/div>\n\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>\u0e1c\u0e28. \u0e14\u0e23.\u0e2d\u0e25\u0e34\u0e2a\u0e32 \u0e14\u0e33\u0e40\u0e19\u0e34\u0e19\u0e2a\u0e27\u0e31\u0e2a\u0e14\u0e34\u0e4c \u0e20\u0e32\u0e04\u0e27\u0e34\u0e0a\u0e32\u0e0a\u0e35\u0e27\u0e27\u0e34\u0e17\u0e22\u0e32 \u0e1c\u0e39\u0e49\u0e14\u0e33\u0e40\u0e19\u0e34\u0e19\u0e01\u0e32\u0e23\u0e23\u0e48\u0e27\u0e21 Jeffrey W. Tyner Tamilla Nechiporuk \u0e01\u0e32\u0e23\u0e28\u0e36\u0e01\u0e29\u0e32 Genome-wide CRISPR screen \u0e23\u0e30\u0e1a\u0e38\u0e15\u0e31\u0e27\u0e04\u0e27\u0e1a\u0e04\u0e38\u0e21\u0e01\u0e32\u0e23\u0e17\u0e33\u0e07\u0e32\u0e19\u0e02\u0e2d\u0e07 MAPK \u0e41\u0e25\u0e30 MTOR pathways \u0e17\u0e33\u0e2b\u0e19\u0e49\u0e32\u0e17\u0e35\u0e48\u0e40\u0e1b\u0e47\u0e19\u0e15\u0e31\u0e27\u0e01\u0e33\u0e2b\u0e19\u0e14\u0e01\u0e32\u0e23\u0e14\u0e37\u0e49\u0e2d\u0e22\u0e32 sorafenib \u0e43\u0e19\u0e21\u0e30\u0e40\u0e23\u0e47\u0e07\u0e40\u0e21\u0e47\u0e14\u0e40\u0e25\u0e37\u0e2d\u0e14\u0e02\u0e32\u0e27\u0e41\u0e1a\u0e1a\u0e40\u0e09\u0e35\u0e22\u0e1a\u0e1e\u0e25\u0e31\u0e19\u0e0a\u0e19\u0e34\u0e14\u0e21\u0e31\u0e22\u0e2d\u0e35\u0e25\u0e2d\u0e22\u0e14\u0e4c A genome-wide CRISPR screen identifies regulators of MAPK and MTOR pathways that mediate resistance to sorafenib in acute myeloid leukemia \u00a0 \u00a0 \u00a0&#8230;<\/p>\n","protected":false},"author":21,"featured_media":14303,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"elementor_header_footer","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[849,635],"tags":[1472,1476,1483,1491,1493],"class_list":["post-14106","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-pls","category-articles","tag-genome-wide-crispr-screen","tag-mapk","tag-mtor-pathways","tag--sorafenib","tag-1493"],"_links":{"self":[{"href":"https:\/\/science.mahidol.ac.th\/simple-science\/wp-json\/wp\/v2\/posts\/14106","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/science.mahidol.ac.th\/simple-science\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/science.mahidol.ac.th\/simple-science\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/science.mahidol.ac.th\/simple-science\/wp-json\/wp\/v2\/users\/21"}],"replies":[{"embeddable":true,"href":"https:\/\/science.mahidol.ac.th\/simple-science\/wp-json\/wp\/v2\/comments?post=14106"}],"version-history":[{"count":36,"href":"https:\/\/science.mahidol.ac.th\/simple-science\/wp-json\/wp\/v2\/posts\/14106\/revisions"}],"predecessor-version":[{"id":15128,"href":"https:\/\/science.mahidol.ac.th\/simple-science\/wp-json\/wp\/v2\/posts\/14106\/revisions\/15128"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/science.mahidol.ac.th\/simple-science\/wp-json\/wp\/v2\/media\/14303"}],"wp:attachment":[{"href":"https:\/\/science.mahidol.ac.th\/simple-science\/wp-json\/wp\/v2\/media?parent=14106"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/science.mahidol.ac.th\/simple-science\/wp-json\/wp\/v2\/categories?post=14106"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/science.mahidol.ac.th\/simple-science\/wp-json\/wp\/v2\/tags?post=14106"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}